Research at UVA: The Quest to Conquer Alzheimer’s Disease

Date & Time

June 7, 2019 @ 1:00 p.m. - 2:00 p.m.


Minor Hall, Room 125
McCormick Road
Charlottesville, VA 22903



Alzheimer’s disease has been the most expensive disease in the U.S. since 2013. It cost American society approximately $260 billion in 2017, a sum that will rise to more than $1 trillion by 2050 unless methods to prevent Alzheimer’s disease or significantly slow its progression can be developed soon. To that end, the Bloom lab recently obtained evidence that memantine (Namenda®), an FDA-approved drug for modest and temporary symptom relief in advanced AD patients, may also be able to prevent Alzheimer’s disease. Bloom will discuss how that discovery might lead to a clinical trial to test if daily memantine treatment beginning years before Alzheimer’s disease symptoms develop can prevent or delay symptom onset.


George Bloom

Professor of Biology, Cell Biology, and Neuroscience; Chair of Biology, College and Graduate School of Arts & Sciences

George Bloom moved to the University of Virginia in August, 2000, after spending 16 years at the University of Texas Southwestern Medical Center at Dallas, where he left as a Professor in the Department of Cell Biology. He is currently a Professor in both the College of Arts and Sciences (Department of Biology) and the School of Medicine (Department of Cell Biology). His alma mater, the University of Pennsylvania, awarded him a B.A. in Biology and History in 1973, and a Ph.D. in Biology in 1979. Dr. Bloom’s career originally focused on fundamental cell biological questions, most notably how mammalian cells move and change shape, and transport cellular building blocks from place to place within the cell. More recently, this basic science approach led directly to more clinically relevant research on Alzheimer’s disease, which is now the dominant theme in his lab. He has authored more than 80 scientific papers, has served on grant review panels for the NIH, the Alzheimer’s Association, the American Cancer Society and the Department of Defense, and is currently an Associate Editor for the journal Cytoskeleton. His lab has been supported by grants from the NIH, the Owens Family Foundation, the Alzheimer’s Association, the Cure Alzheimer’s Fund and the American Cancer Society, among other funding agencies. Dr. Bloom lives in Charlottesville with his wife, Patricia Bloom. If he is not working in his lab in the new Physical and Life Sciences Building, you might find him fly fishing for trout on a nearby Blue Ridge Mountain stream.